During a home inspection you will be asked to absorb a lot.   This vast amount of information combined with the seller's disclosure and what you notice yourself can make the experience overwhelming.   Often a serious problem can be corrected inexpensively to protect both life and property.  In most cases the home inspection report will primarily include maintenance recommendations, life expectancies and minor imperfections.  However, the inspection issues that really matter and that should be addressed are:   

 Major defects of the home. An example of this would be a structural failure.
 Things that lead to major defects. A small roof-flashing leak, for example.
 Things that may hinder your ability to finance legally occupy or insure the home.
 Safety hazards, such as an exposed, live buss bar at the electric panel.

It is important to understand that sellers are not obligated to repair everything mentioned in the inspection report. Keep things in perspective,  No home is perfect!  It is inappropriate to demand that a seller address deferred maintenance, conditions already listed on the seller's disclosure, or "nit-picky items."